They can result in severely low red blood cells and platelets in your body. 6 disease interactions. Moderately clinically significant. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that youre taking. We study millions of patients and 5,000 more each day. Take Valtrex exactly as it was prescribed for you. Side effects include headache, rash, itching, nausea, vomiting, and others. For seniors: The kidneys of older adults may not work as well as they used to. Moderately clinically significant. On average, six Americans die every day from alcohol toxicity. Talk with your doctor about breastfeeding your child. Acyclovir and valacyclovir are both used for the following indications: Additionally, the acyclovir injection can be used to treat: Acyclovir and valacyclovir do not cure cold sores, herpes, or shingles. The more common side effects of nitrofurantoin can include: nausea vomiting loss of appetite stomach pain diarrhea numbness in your hands and feet pain in your hands and feet weakness dizziness. Of the total drug interactions, Keep these considerations in mind if your doctor prescribes nitrofurantoin oral capsule for you. Nitrofurantoin oral capsule is used for short-term treatment of urinary tract infections. Our phase IV clinical studies alone cannot establish cause-effect relationship. If you stop taking the drug suddenly or dont take it at all: Your urinary tract infection may not go away and may get worse. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. What are the important side effects of Macrobid (nitrofurantoin), Macrobid (nitrofurantoin) side effects list for healthcare professionals. For treatment of urinary tract infections: Adults and teenagers50 to 100 milligrams (mg) every six hours. Never try to catch up by taking two doses at once. All products at our site are available to be shipped - that means we have them in stock and can ship them to you within 1-2 business days after payment clearance. What drugs interact with Macrobid (nitrofurantoin)? I woke up this morning with a sore throat, coughing, and sneezing the general indications of the delta crud as we call it. What to do if you miss a dose: Take your dose as soon as you remember. The use of the eHealthMe site and its content is at your own risk. privacy practices. Drugs such as diclofenac ( Zorvolex) are more likely to affect the liver, so monitoring of the liver is recommended. Macrobid and generic Macrobid can be stored between 59F and 86F (15C and 30C). Your dosage, drug form, and how often you take the drug will depend on: The dose of both acyclovir and valacyclovir varies depending on your body weight and the condition you are treating. Be sure to avoid doing this when the weather is very hot or very cold. These medications are not usually taken together. If you have kidney disease, talk to your doctor about adjusting your acyclovir or valacyclovir dose. The guidance in this document is based on the drug-drug interaction potential of the FDA-authorized 5-day course of ritonavir-boosted nirmatrelvir. Mayo Clinic does not endorse companies or products. health information, we will treat all of that information as protected health There arent enough studies done in humans to show if the drug poses a risk to the fetus. This medicine works best when taken early in the course of an infection, within the first 72 hours. You should take valacyclovir within 24 to 48 hours of the onset of symptoms. Macrobid, Macrodantin, and Furadantin should not be used near the time of delivery (38-42 weeks gestation) since it interferes with the immature enzyme systems in the red blood cells of newborns, potentially damaging the cells and resulting in anemia. The study uses data from the FDA. What Is the Difference Between a Bladder Infection vs. UTI? All information is observation-only. This raises your risk of side effects. Further, both drinking and Valtrex can cause nausea, potentially worsening that side effect. Ritonavir-boosted nirmatrelvir should not be given within 2 weeks of administering a strong CYP3A4 inducer (e.g., St. John's wort, rifampin). 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Neither medication is better than the other, but if someone cant tolerate Valtrex or has an underlying medical condition that prevents them from taking it, acyclovir is another good option. There are 10 disease interactions with progesterone which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. It is often used in herpes zoster. Bactrim has active ingredients of sulfamethoxazole; trimethoprim. * Approximation only. Do not double doses. include protected health information. How To Cure A Uti Naturally Without Antibiotics, What Antibiotic Do You Take For A Bladder Infection. Also, angioedema; maculopapular, erythematous, or eczematous eruptions; anaphylaxis; arthralgia; myalgia; drug fever; chills; and vasculitis (sometimes associated with pulmonary reactions) have been reported. Different individuals may respond to medication in different ways. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). it damages the myelin sheath): 9 people, 14.06%, Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 7 people, 10.94%, Sinusitis (inflammation of sinus): 6 people, 9.38%, Spondyloarthropathy (any joint disease of the vertebral column): 5 people, 7.81%, Psoriasis (immune-mediated disease that affects the skin): 5 people, 7.81%, Multiple Allergies (allergy to multiple agents): 5 people, 7.81%. is it ok to take ibuprofen with amoxicillin? Because viruses inside cells are harder to target, antiviral drugs are more challenging to develop. The study uses data from the FDA. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. eHealthMe is studying from 28,892 Valacyclovir users for its effectiveness, alternative drugs and more. Tell your doctor if a child taking this medicine cannot swallow the tablet. Avoid combinations; the risk of the interaction outweighs the benefit. See additional information. Bacteria such as E. coli or Pseudomonas can cause a urinary tract infection (UTI). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. If youre struggling with your drinking habits, addiction treatment can help you live a healthier, alcohol-free life. For seniors: The kidneys of older adults may not work as well as they used to. Portions of this document last updated: Feb. 01, 2023. All information is observation-only. In case of overdose, get medical help or contact a Poison Control Center immediately. Read Also: Can Antibiotics Cause Thrush In Mouth. THE RISK IS GREATER WHEN CHRONIC PULMONARY REACTIONS ARE NOT RECOGNIZED EARLY. Nitrofurantoin helps kill the bacteria that cause urinary tract infections. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Macrobid and its generic form: These drugs are not used for the prevention of urinary tract infections. Enter other medications to view a detailed report. Before you take fluconazole to treat a yeast infection, check with your healthcare professional or pharmacist about potential interactions with medicines you may already be taking, or check for medication interactions online. To provide you with the most relevant and helpful information, and understand which Nitrofurantoin can cause red blood cell problems in a newborn. This may help reduce upset stomach symptoms and allow the drug to work better. other information we have about you. View interaction reports for progesterone and the medicines listed below. information is beneficial, we may combine your email and website usage information with 2023 eHealthMe.com. Usually avoid combinations; use it only under special circumstances. Adult and Pediatric Dose Forms and Strengths, Recommended Reading: Is The Flu Treated With Antibiotics. Symptoms can include: Research in animals has not shown a risk to the fetus when the mother takes the drug. There are 182 drugs known to interact with Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Nitrofurantoin is a prescription drug that comes as an oral capsule and an oral suspension. This content does not have an Arabic version. The phase IV clinical study analyzes what interactions people who take Bactrim and Macrobid have. Minimally clinically significant. a history of kidney transplant or bone marrow transplant. Furadantin nitrofurantoin suspension. The choice between acyclovir and valacyclovir depends on a few factors, including side effects and how often you take the medication. This reaction occurs most frequently in persons with a deficiency of an enzyme called glucose--6-phosphate dehydrogenase that is very important to the survival of red blood cells. Do not give this medicine to a child without medical advice. A class of drugs is a group of medications that work in a similar way. A prescription for this medication is refillable. Portions of this document last updated: Feb. 01, 2023. Acute pulmonary reactions are commonly manifested by fever, chills, cough, chest pain, dyspnea, pulmonary infiltration with consolidation or pleural effusion on x-ray, and eosinophilia. You may opt-out of email communications at any time by clicking on Dont worry about airport X-ray machines. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. information and will only use or disclose that information as set forth in our notice of To make sure Valtrex is safe for you, tell your doctor if you have: HIV/AIDS, or other conditions that can weaken the immune system or. Macrobid, Macrodantin, and Furadantin are distributed into breast milk and should be used with caution in women who are breastfeeding. Also Check: Antibiotics To Avoid With Crohns Disease. Talk to your doctor if you breastfeed your child. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. You can compare the medications here. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. 64 people who take Macrobid and Valacyclovir together, and have interactions are studied. For this reason, women who are pregnant should not take this drug: Call your doctor if you become pregnant while taking this drug. For pregnant women: During weeks 037 of pregnancy, nitrofurantoin is a category B pregnancy drug. Examples of these drugs include: Disclaimer: Our goal is to provide you with the most relevant and current information. It's not an antibiotic, but it should also be avoided in people allergic to sulfonamide antibiotics. Nitrofurantoin can also cause damage to the sensory nerves of the arms and legs (peripheral neuropathy), which can cause tingling in the extremities. Tell your doctor or health care professional if your symptoms do not start to get better after 1 week. Avoid combinations; the risk of the interaction outweighs the benefit. Further, alcohol can trigger migraines. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Yes, antiviral drugs can keep you from getting certain viral infections after a suspected or known exposure. Alcohol poisoning is unfortunately common with excessive alcohol intake. There are more viruses than antiviral drugs to treat them. This can cause your body to process drugs more slowly. This site complies with the HONcode standard for trustworthy health information: verify here. How to tell if the drug is working: The symptoms of your urinary tract infection should get better. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Learn about home remedies that may help treat UTIs. Hypersensitivity reactions represent the most frequent spontaneously-reported adverse events in worldwide postmarketing experience with nitrofurantoin formulations. This information is not a substitute for medical advice. These formulations are easier to use with children or people who have trouble swallowing pills. Headaches are also a common hangover symptom. It is often used in urinary tract infection. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. We comply with the HONcode standard for trustworthy health information. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Does valacyclovir interact with my other drugs? RADIOLOGIC AND HISTOLOGIC FINDINGS OF DIFFUSE INTERSTITIAL PNEUMONITIS OR FIBROSIS, OR BOTH, ARE ALSO COMMON MANIFESTATIONS OF THE CHRONIC PULMONARY REACTION. If you miss doses or dont take the drug on schedule: Your medication may not work as well or may stop working completely. TTP or HUS can cause death. Minimally clinically significant. It can make your liver damage worse. CHRONIC, SUBACUTE, OR ACUTE PULMONARY HYPERSENSITIVITY REACTIONS MAY OCCUR WITH THE USE OF NITROFURANTOIN. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Our company strives to maintain and improve every phase of our business and satisfy needs of our customers. Headache is by far the most common side effect of Valtrex, impacting up to 38% of people. Call your doctor right away if you have serious side effects. Bulging fontanels, as a sign of benign intracranial hypertension in infants, have been reported rarely. Dermatologic: Exfoliative dermatitis and erythema multiforme (including Stevens-Johnson syndrome) have been reported rarely. Your symptoms may improve before the infection is completely cleared. All rights reserved. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. In the last 2 decades, influenza-associated morbidity and mortality have increased, in part as a result of an aging population, which highlights the need for enhanced treatment. But if you remember just a few hours before your next scheduled dose, take only one dose. Drug interactions of Macrobid, Macrodantin, and Furadantin include probenecid, sulfinpyrazone, magnesium trisilicate antacids, live tuberculosis vaccines (BCG vaccine) and live typhoid vaccines, and quinolone antibiotics. MedicineNet does not provide medical advice, diagnosis or treatment. Dont put this medication in your cars glove compartment or leave it in the car. Examples of drugs that can cause interactions with nitrofurantoin are listed below. progesterone, along with All rights reserved. The phase IV clinical study analyzes what interactions people who take Bactrim and Macrobid have. Valacyclovir can pass into breast milk and may harm a nursing baby. Macrodantin and its generic form are safe for use in children older than 1 month. You may need to decide whether to stop breastfeeding or stop taking this medication. Patients in the study may take other drugs besides Bactrim and Macrobid. Antacids containing magnesium trisilicate, when administered concomitantly with nitrofurantoin, reduce both the rate and extent of absorption. Nitrofurantoin oral capsule is available as the brand-name drugs Macrobid and Macrodantin. Progesterone Interactions There are 182 drugs known to interact with progesterone, along with 10 disease interactions, and 4 alcohol/food interactions. However, they relieve the symptoms of the outbreaks and help the lesions heal faster. Overdoses of up to 20 grams have been linked to the development of temporary neurological issues, including mental status changes, seizures and hallucinations. Taking it again could be fatal (cause death). Each antiviral only works against a specific virus. Nitrofurantoin oral capsule may cause drowsiness. However, herpes virus can be passed from an infected mother to her baby during childbirth. Summary: Drug interactions are reported among people who take Bactrim and Macrobid. I was just wondering if it was safe to take them together, or if I should just stick with one or the other. Additional clinical adverse events reported as possibly or probably drug-related occurred in less than 1% of patients studied and are listed below within each body system in order of decreasing frequency: Gastrointestinal: Diarrhea, dyspepsia, abdominal pain, constipation, emesis, Neurologic: Dizziness, drowsiness, amblyopia, Respiratory: Acute pulmonary hypersensitivity reaction. Available for Android and iOS devices. Valtrex and alcohol share some common side effects. Drug information provided by: IBM Micromedex. Nitrofurantoin is also available in an oral suspension, Nitrofurantoin oral capsule is used to prevent and treat, yellowing of your skin or the whites of your eyes, numbness or tingling in your hands and feet. There are 183 drugs known to interact with The incubation period for a UTI ranges from three to eight days. Possible serious side effects include: Lung injury. The resulting increase in nitrofurantoin serum levels may increase toxicity, and the decreased urinary levels could lessen its efficacy as a urinary tract antibacterial. Your dosage, drug form, and how often you take the drug will depend on: The kidneys of older adults may not work as well as they used to. You can take acyclovir with or without meals, but it is best to take the medication with a full glass of water. The more common side effects of nitrofurantoin can include: If these effects are mild, they may go away within a few days or a couple of weeks. Other drugs may interact with valacyclovir, including prescription and over-the-counter medicines, vitamins, and herbal products. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. It is often used in urinary tract infection. Take your medicine as directed to best control your infection. The following information includes only the average doses of this medicine. Of the total drug interactions, a kidney transplant or bone marrow transplant. Conditions such as renal impairment (creatinine clearance under 60 mL per minute or clinically significant elevated serum creatinine), anemia, diabetes mellitus, electrolyte imbalance, vitamin B deficiency, and debilitating diseases may increase the possibility of peripheral neuropathy. This is also a common Valtrex side effect, experienced by approximately 15%of people on the drug. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Do not open, crush, or chew the capsule before swallowing it. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Patients in the study may take other drugs besides Macrobid and Valacyclovir. 2023 eHealthMe.com. This can be harmful or prevent the drug from working well. If you miss a dose of this medicine, take it as soon as possible. As a result, more of a drug stays in your body for a longer time. You should not use Valtrex if you are allergic to valacyclovir or acyclovir . Alcohol can impair your immune system, making your infection harder to treat. Some reports may have incomplete information. That means it wont work for you anymore. Length of treatment may vary. There have been sporadic reports of pseudomembranous colitis with the use of nitrofurantoin. Symptoms include: Fortunately, the symptoms usually resolve within a week if the medication is stopped. Advertising revenue supports our not-for-profit mission. Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. This information is not a substitute for medical advice. eHealthMe is studying from 8,326 Macrobid users for its effectiveness, alternative drugs and more. Highly clinically significant. This is especially important if you experience recurrent vaginal yeast infections, since your healthcare professional . Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Terms of Use. Is the ketogenic diet right for autoimmune conditions? Review/update the * Approximation only. Read Also: What Is Antibiotic Resistant Bacteria. We avoid using tertiary references. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Email this report to a friend, doctor, or patient. amoxicillin, doxycycline, cephalexin, ciprofloxacin, levofloxacin, Augmentin, ceftriaxone, Bactrim, Keflex, sulfamethoxazole / trimethoprim. For women who are breastfeeding: Nitrofurantoin may pass into breast milk and cause side effects in a child who is breastfed. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. There are other drugs available to treat your condition. Animal studies do not always predict the way humans would respond. Infants younger than 1 month of ageUse is not recommended. Can you take valtrex and Macrobid at the same time? Consult your doctor. If your symptoms are severe, call 911 or go to the nearest emergency room. Use this medicine for the full prescribed length of time. This information is not a substitute for medical advice. generic drugs) are not considered. It can elevate trazodone levels, worsening side effects like dizziness and low blood pressure.