All Rights Reserved. Here are the odds for all the games for Week 1 of the 2021 NFL season. "Arizona figures to be one of our biggest needs in the late games. No one's playing the Patriots right now," Shelton said. All Week 1 NFL odds are according to DraftKings Sportsbook and will vary from outlet to outlet. Ticket count is dead even, while the Under is taking 69% of cash. Over 51.5 BetMGM: -110 ET THURSDAY: Several hours ahead of kickoff, Caesars Sports has Buffalo as a 2.5-point road favorite against Los Angeles. NFL Week 1 Picks 2021. He is paired with first overall pick Trevor Lawrence as the new face of the franchise. "Despite the Rams winning the Super Bowl and being at home for this game, the line flipped pretty quickly to Bills favored, and it makes sense," said John Murray, executive director of The SuperBook. Not only that, but former Rams defensive coordinator Brandon Staley is at the helm and will need time to implement his system. Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned over $7,500 since its inception, and find out. Bettors that relied on favorites to carry them to victory were disappointed, as a record number of underdogs covered the spread.. The line returned to -6 Wednesday, but it's been stable at -6.5 since FRiday evening. The Dolphins continue to be a 3-point favorite at The SuperBook. Since then, the Broncos backed up to -6 a couple of times, but they've been stable at -6.5 since Tuesday morning. The opening line had Washington -1.5, which I would have bet, making this a surefire pick for me. But 2020 still ended in disappointment for Tennessee in the form of a first-round exit courtesy of the Ravens. One spread has hit as low as a pick'em, while another reached 8.5 before falling slightly. Week 1 of the 2021 NFL season features multiple mouthwatering matchups, including Cowboys vs. CBS Sports is a registered trademark of CBS Broadcasting Inc. Commissioner.com is a registered trademark of CBS Interactive Inc. site: media | arena: nfl | pageType: stories | New York also upgraded at receiver with the free agent addition of Kenny Golladay and the drafting of Floridas Kadarius Toney, a duo that will pair with Sterling Shepard, Darius Slayton and Evan Engram to give quarterback Daniel Jones a no excuses pass-catching corps. The Lions are another team getting a fresh start, with Dan Campbell now the man in charge in Motown. Tom Brady and the Tampa Bay Buccaneers finished off Sunday's slate of games by beating the Dallas Cowboys. It opened at 52, briefly went to 51.5 and returned to 52. Kliff Kingsbury and Kyler Murray have heard all the detractors and will look to piece everything together in 2021. The Football Team was the proverbial big fish in the small pond that the NFC East became last season after Prescott went down for the Cowboys. The game isnt going to be even close, but with it being Opening Week, the spread never tends to be too big. The Giants held on for the win when Tennessee's Randy Bullock was wide left on a 47-yard field-goal attempt with four seconds to go. Home-field advantage has been and always will be a major factor when betting on pro football. Chase, along with Tee Higgins and Tyler Boyd, give the second-year gunslinger a highly potent trio. On the Baltimore side, you have top-tier roster construction combined with excellent drafts. Phillip Lindsay and Mark Ingram also arrived via free agency to pair with David Johnson, who was serviceable in his first Texans season. Ryan is on the wrong side of 30, but he can decimate this Eagles defense in Week 1. Las Vegas Raiders vs Los Angeles Chargers. The latest Week 1 NFL odds from Caesars Sportsbook list all but one Sunday game with a spread within one score. The Bucs are taking 62% of spread tickets and 70% of spread dollars. Here are our Week 1 picks and predictions still months away from the 2021 NFL season opener. "When it comes to this matchup, the Titans were the No. The Broncos primarily made headlines this offseason for one big reason the quarterback position. Check back regularly for updates. Quarterback Jimmy Garoppolo will get the start for San Francisco, but SportsLine's model is also projecting rookie Trey Lance to get a few opportunities as well. See which other teams to pick here. BETTING: FANTASY : Live Odds. The total went to 43 on Sept. 4, 44 on Sept. 6 and peaked at 45 a couple of times over the past few days. As such, Week 1 NFL betting odds have been posted for this years opening week. Bridgewater will start Week 1 for Denver and will have the benefit of the returning Courtland Sutton, who missed all but one game last season with a knee injury, and a bevy of young pass catchers that includes Jerry Jeudy, Tim Patrick and KJ Hamler. The line backed up to -5.5 a day later, returned to -6 Aug. 24, and it's mostly been at a couple iterations of -6.5 since Aug. 28. Miami opened and closed the regular season against New England and went 2-0 SU and ATS. The Colts had been favored by around 2 points in this one before the initial injury to Wentz, but Seattle has been a slight road favorite over the past month and they continue to be favored at most books. The Cardinals disappointingly dropped their final two games last season to finish 8-8 and out of the postseason, but there were still strides made by Kliff Kingsburys squad after a 5-10-1 season in 2019. The NFL week 1 lock is the Jacksonville Jaguars giving 3 points on the road at the Houston Texans. Buffalo pushed the Kansas City Chiefs to overtime in last season's AFC Divisional Playoffs. At WynnBet, The Chiefs are taking 71% of spread bets and 95% of spread money. Point spread: Lions (+5.5) cover by losing by fewer than 5.5 points (3)Moneyline: Eagles win as -250 favorites (bet $10 to win $14 total); Lions were +190 underdogs (bet $10 to win $29 total)Total scoring over/under: Over 48 points scored by both teams combined (73), Point spread: Ravens (-6.5) covers by winning by more than 6.5 points (15)Moneyline: Ravens win as -303 favorites (bet $10 to win $13.30 total); Jets ware +220 underdogs (bet $10 to win $32 total)Total scoring over/under: Under 44 points scored by both teams combined (33), Miami Dolphins 20, New England Patriots 7, Point spread: Dolphins (-3) cover by winning by more than 3 points (13)Moneyline: Dolphins win as -162 favorites (bet $10 to win $16.15 total); Patriotswere +125 underdogs (bet $10 to win $22.50 total)Total scoring over/under: Under 46.5 points scored by both teams combined (27), Point spread: Bears (+6.5) cover by winning outrightMoneyline: Bears were +220 underdogs (bet $10 to win $32 total); 49ers were -303 favorites (bet $10 to win $13.30 total)Total scoring over/under: Under 37 points scored by both teams combined (29), Jacksonville Jaguars 28, Washington Commanders 22, Point spread: Commanders (-3) cover by winning by more than 3 points (6)Moneyline: Commanders win as -162 favorites (bet $10 to win $16.17 total); Jaguars were +125 underdogs (bet $10 to win $22.50 total)Total scoring over/under: Over 43.5 points scored by both teams combined (50), Indianapolis Colts 20, Houston Texans 20 (OT), Point spread: Texans (+7) cover by playing to a tieMoneyline: Colts were -400 favorites (bet $10 to win $12.50 total); Texans were +280 underdogs (bet $10 to win $38 total)Total scoring over/under: Under 46 points scored by both teams combined (40), Point spread: Bills (-2) cover by winning by more than 2 points (21)Moneyline: Bills win as -138 favorites (bet $10 to win $17.25 total); Rams were +115 underdogs (bet $10 to win $21.50 total)Total scoring over/under: Under 52 points scored by both teams combined (41). We don't have any odds for upcoming NFL games. Bet with your head, not over it. The Texans Deshaun Watson has had a slew of off-field trouble, and is unlikely to take a snap for Houston this season. Dalton will start this game and will have top wideout Allen Robinson back. Both teams missed field-goal attempts in OT. UPDATE 9 P.M. After last night's short stint at 7 drew sharp play on Seahawks +7 (-120), Denver dipped to -6.5. This is one of my favorite picks for Week 1 of the NFL. Following an NFL season that conformed to the unique realities of playing a professional team sport during a pandemic, the 2021 campaign promises a return to what could be considered near normal. Open Result. NFL Week 1 Odds Denver Broncos vs Seattle Seahawks Russell Wilson leads his new team, the Broncos, against his former team, the Seahawks. If you place $100 in NFL bets during the month, you will win a FREE NFL jersey! And at +1300, Knox is also tops in tickets and money on the prop of player to score the first TD. The model has also made the call on who wins and covers in every other game on the Week 1 NFL schedule, and it's calling for a Super Bowl contender to go down hard. The number nudged back to -2 a couple of times over the past couple of days, and it's been at -2.5 since late this afternoon. So what NFL picks can you make with confidence? Right out of the gate, we got a big game. And a big move came this morning on this matchup. But today's move had more to it than that. Detroit is a 5.5-point underdog in the latest Week 1 NFL odds at Caesars Sportsbook, one of the larger NFL spreads this week. That would be the Tampa Bay Buccaneers who showed a profit of $758 on the opening odds prices for $100 bets each week. Hilton is on IR for at least the first three weeks due to a neck issue. Top US sportsbooks have NFL Week 1 odds available to wager on now with a full Sunday slate on tap. ET SUNDAY: Miami opened as a 3-point favorite at WynnBet, dipped to -2.5 in mid-July and peaked at -3.5 Tuesday. But that includes a low-six-figure wager on Buffalo -2.5. The Seahawks weathered a storm of offseason turmoil surrounding franchise signal-caller Russell Wilson following an unceremonious Wild Card round upset at the hands of the Rams. August 12, 2021: Pre-Season Week 1: August 19, 2021: Pre-Season Week 2: August 26, 2021: Pre-Season Week 2: August 31, 2021: Roster Cuts: September 9, 2021: Regular Season Week 1: . footballlocks.com rank has been stable with no relevant variation over the last 3 months. "There's almost zero money on the Patriots here in Nevada. ET WEDNESDAY: Back in mid-May, Tampa Bay opened as a 2-point road fave vs. Dallas at PointsBet USA. UPDATE 6 P.M. 21+: TheLines.com and all content herein is intended for audiences 21 years and older. ET THURSDAY: With kickoff an hour away, DraftKings has the Bills at -2.5, representing a 3.5-point shift from the mid-May opener of Rams -1. The Week 1 NFL schedule has arrived and oddsmakers are expecting plenty of tight games. Arizona Cardinals (+2.5) at Tennessee . Subscribe to Vegas Odds newsletter and always stay tuned. The Over is taking 70% of early tickets/83% of early dollars. We figured out each implied total by dividing the over/under number in half, then dividing the point spread in half and subtracting the latter from the former. UPDATE 7:45 P.M. Another one of the top Week 1 NFL picks from the model: The Panthers (-4) cover as home favorites against the Jets. The fact that Gang Green will roll out a rookie QB and Darnold gets a crack at his old teammates makes this line another very noteworthy one to potentially jump on, although Carolina was just 2-6 at home straight up and ATS in 2020. Tyrod Taylor will helm an air attack that lost Will Fuller in free agency but still sports Brandin Cooks, Randall Cobb and offseason arrival Chris Conley, wholl face his former Jags teammates in this Week 1 game. closed as a 7-point home favorite and lost to Cincinnati 27-24 in overtime. The public is on the Bills, and they're playing Bills moneyline, too. 2021 NFL Week 1 odds: 49ers open as biggest favorites, eight games have spread of three points or less Even if the Rams offense messes it up (they wont! New England then lost longtime offensive coordinator Josh McDaniels, now the Raiders' head coach. Week 1 NFL panel picks: Spreads, totals, locks to kick off 2021 Video is unavailable. Its worth noting that San Fran was 7-1 straight up and 6-2 ATS on the road with an average margin of victory of 8.4 points and ATS +/- of +6.8 points during its much healthier 2019 campaign. "This is gonna be one of the biggest public plays of all time in Week 1," Shelton said. The model has the Vikings (+1.5) covering as home underdogs in well over 50 percent of simulations. I anticipate that when we get closer to game time, the public is going to see those two teams and most likely bet Over. "The action today was likely from a professional syndicate, causing the line to move," Manica said. Taylor himself hasnt started a game since Week 1 of 2020. He now has Terry McLaurin, Curtis Samuel, Antonio Gibson, Logan Thomas, and a stable of young playmakers to target. Meanwhile, the 2016 second overall pick is already facing some limitations in terms of the offensive personnel around him, as left tackle Eric Fisher is out with an Achilles injury and T.Y. ET MONDAY, AUG. 29: After two straight Super Bowl trips and one championship, Kansas City went 14-6 SU/10-10 ATS last year, including postseason play. The Bucs have been fairly stable at -1.5 since Aug. 16. The Bills feature a high-octane offense led by QB Josh Allen, who was outstanding in his last outing. That could lead to a mismatch in the trenches. A talented Buffalo defense largely enjoys continuity as well. ET SUNDAY:About three hours before kickoff, Kansas City is a 6.5-point favorite at Caesars Sports. "No movement here on the point spread," Murray said. Caesars went straight to -5.5, then onto -6.5 by Tuesday evening. Date. Road Open Spread. The likes of Miles Sanders and rookie Kenneth Gainwell are among those that could support Hurts with a strong ground attack. BettingData's NFL point spreads and odds page features full, compact and classic viewpoints and our members get to see historical NFL odds. The opening line had Washington -1.5, which I would have bet, making this a surefire pick for me. The Steelers had what was arguably one of the more unusual seasons in franchise history in 2020, racing out to an 11-0 start before stumbling to a 1-4 mark down the stretch and then quickly getting ousted in the postseason by the Browns in a Wild Card loss at Heinz Field. 5.5. Jaylen Waddle will join fellow new arrival (via free agency) Will Fuller to give the Fins the outside speed theyve sorely lacked for some time. On Aug. 24, Tampa hit its low point of -1, then rebounded to -2.5 by Tuesday. On the other side of the field, Washington continues to ascend after an impressive playoff run last year albeit with a 7-9 record in the dumpster fire that was the NFC East. The front office seems focused on the 2021 draft more than the 2020 season. Darrell Henderson, who rushed for 624 yards on 147 carries in 2020, should receive the brunt of the carries for the Rams with Akers on the shelf. There has been no line movement from opening to today. Another incremental step forward could vault Buffalo past the Chiefs, especially if Stefon Diggs is able to somehow replicate or exceed last seasons jaw-dropping 127-1,535-8 line. WynnBet was at -4 and moved straight to -6. ET SUNDAY: Four days before this matchup kicks off the regular season, BetMGM Nevada has the Bills -2.5 in the NFL Week 1 odds market. Guys like Aaron Donald, Jalen Ramsey, and the rest are going to bring hellfire to the Chicago offense. We take responsible gambling very seriously and never encourage those underage to participate. Can't miss first week offers He knows Green Bay's scheme as well as anyone and will only add to a pass rush which accumulated the second-most sacks (51) last year. I dont expect this to be a big decision for the book, but I do think its one of the most interesting games of Week 1. You'd think the defending champs opening at home would lead to L.A. being the favorite. The Bucs are landing 70% of spread bets for Sunday Night Football, but that's translating to just 55% of spread dollars. Flores already had Miami at 10-6 and within an inch of the postseason last year, and theyll kick off a campaign they hope will lead to the franchises third playoff appearance since the 2008 season. Enter Sam Darnold, acquired via trade with the Jets, who like Wentz, is a one-time top 3 quarterback selection looking to establish himself elsewhere this coming season. UPDATE 10 P.M. Pro Football Network strives to passionately deliver purposeful, captivating, and exceptional football content. The total moved from 52 to 52.5, but has since slid down to 50. And as noted above, the Raiders have a new coach in Josh McDaniels. And that outing was in arguably one of the best NFL playoff games ever. And which Super Bowl contender goes down hard? The defending Super Bowl champion Los Angeles Rams hosted the Buffalo Bills, who are the favorite in this season's Super Bowl odds market. The Eagles will look for another dominant performance when the teams square off in a rematch on Sunday during the Week 1 NFL schedule. That letdown was in no small part due to QB Kyler Murray missing a few weeks with an ankle injury. Baltimore signed free agents Devonta Freeman, Latavius Murray and LeVeon Bell in response to the latest back, Gus Edwards, going down. CLAIM OFFER section: | slug: nfl-odds-lines-picks-spreads-best-bets-predictions-for-week-1-2021-top-model-backing-49ers-panthers | sport: football | route: article_single.us | Pick: Washington +1.5 More NFL odds, picks, and predictions for Week 1. Las Vegas ultimately got it with a 35-32 overtime victory, winning on a final-seconds field goal. The Brian Flores Era is going about as well as owner Stephen Ross could have hoped when he took a chance on the first-time head coach two off-seasons ago. Head over to the NFL section on the FOX Sports app and website for all the latest news, and make sure to favorite the NFL and your favorite team or teams! That's after opening this contest a pick 'em back in June. So ideally, the book is rooting for a Tampa win and a Dallas cover, in that very narrow 2.5-point frame. McIntyre: "Im not a trend bettor, but one worth looking at in Week 1: Teams that didnt make the playoffs last season against teams that did. The total opened at 45, bottomed out at 44 in early July and peaked at 47 a week ago. Still, that wasn't enough to save Brian Flores' job, and Mike McDaniel is the new coach. All of the Week 1 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best Week 1 NFL picks now. Below, we've compiled a table of Week 1 implied totals for each team at DraftKings Sportsbook. After spending most of the summer at -4.5, the Broncos advanced to -5.5 and then -6 on Aug. 21. Read which dogs Jason McIntyre thinks have a chance to bark, Sammy P's sharp college football and NFL wagers, Cowboys lose game to Buccaneers, Dak Prescott to injury in disastrous opener. The Bucs made a couple trips to -2 over the next two months, then dipped to -1.5 Aug. 5. Ryan Fitzpatrick will be under center, and if there is anything we know about FitzMagic, you do not bet against him. Week 1 NFL odds, picks, schedule, how to watch, streaming: Expert picks against the spread, survivor, more The NFL season has finally returned, and CBSSports.com and SportsLine are. Young tight end Irv Smith also made strides, but the defense long a hallmark of coach Mike Zimmers teams faltered badly while allowing 29.7 points and 393.2 yards per game. The total opened at 51.5, got to 52.5 in late July, then receded to 49.5 by Aug. 20. Miami should also be strong this year but the Pats will have the home crowd behind them while tackling is always sketchy at the start of the campaign so their running game has the potential to destroy the Dolphins. ET MONDAY: Thirty minutes pre-kick, BetMGM has the Broncos at -6 (-115), down a point from the Sunday night peak of -7 (even). On Aug. 7, the Bills reached -2.5, where they've been ever since. News over the summer initially got bettors on the Chiefs' bandwagon. The offense remains essentially the same, but the defense could be even better with key offseason additions Jadeveon Clowney, John Johnson and dynamic rookie linebacker Jeremiah Owusu-Koramoah. Relied on favorites to carry them to victory were disappointed, as a pick 'em back in.. That letdown was in arguably one of the gate, we & # x27 ; ve compiled a table Week... Has the Vikings ( +1.5 ) covering as home underdogs in well 50. 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