NIH J Proteomics. This study compared the phospholipases A2 (PLA2S) present in four commercially available venoms of Russell's viper subspecies by HPLC fractionation and partial sequence analysis. 1994 Mar 9;710:120-5. doi: 10.1111/j.1749-6632.1994.tb26619.x. Front Pharmacol. 2011 Feb;104(2):97-108. doi: 10.1093/qjmed/hcq214. Animal Toxins as Therapeutic Tools to Treat Neurodegenerative Diseases. 1995 Jan;33(1):63-76. doi: 10.1016/0041-0101(94)00133-s. Pla D, Sanz L, Quesada-Bernat S, Villalta M, Baal J, Chowdhury MAW, León G, Gutiérrez JM, Kuch U, Calvete JJ. Maung-Maung-Thwin, Gopalakrishnakone P, Yuen R, Tan CH. Gołaszewska A, Bik W, Motyl T, Orzechowski A. Int J Mol Sci. Daboia (Daboia, Wikipedia) is a monotypic genus of venomous Old World viper. Dilute Russells Viper Venom Time (DRVVT) is a blood test that detects the presence of lupus anticoagulants (LA), which are autoantibodies that interfere with the blood clotting process. Toxins (Basel). This study provides evidence for the presence of two types of Russell's viper. The venom PLA2S of D. r. russelli (southern India) used in a previous study appear to be the same as those of D. r. pulchella (Sri Lanka), while the venom PLA2S of D. r. russelli (Pakistan) and D. r. siamensis (Burma and Thailand) resemble those of D. r. formosensis (Taiwan). 2017 Jan;31(1):11-19. doi: 10.1007/s12640-016-9650-4. Lee CH, Lee YC, Lee YL, Leu SJ, Lin LT, Chen CC, Chiang JR, Mwale PF, Tsai BY, Hung CS, Yang YY. Epub 2019 Jul 17. Clinical and Pharmacological Investigation of Myotoxicity in Sri Lankan Russell's Viper (Daboia russelii) Envenoming. Epub 2010 Nov 28. Get the latest research from NIH: https://www.nih.gov/coronavirus. 2017 Oct 27;9(11):347. doi: 10.3390/toxins9110347. You need this test when you have signs of a blood clot. “Stypven”, Burroughs-Wellcome Pharma). This study compared the phospholipases A2 (PLA2S) present in four commercially available venoms of Russell's viper subspecies by HPLC fractionation and partial sequence analysis. It was widely used as a styptic to clot minor wounds when razor blades were more commonly used for shaving (e.g. Daboia russelli formosensis (Taiwan). Epub 2016 Jul 11. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Phylovenomics of Daboia russelii across the Indian subcontinent. Antonypillai CN, Wass JA, Warrell DA, Rajaratnam HN. Neurotox Res. Single Chain Antibody Fragment against Venom from the Snake Daboia russelii formosensis. Silva A, Johnston C, Kuruppu S, Kneisz D, Maduwage K, Kleifeld O, Smith AI, Siribaddana S, Buckley NA, Hodgson WC, Isbister GK. This site needs JavaScript to work properly. 2019 Sep 15;207:103443. doi: 10.1016/j.jprot.2019.103443. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Bioactivities and comparative in vivo neutralization and in vitro third-generation antivenomics of antivenoms against venoms from India, Bangladesh and Sri Lanka. 2016 Dec 2;10(12):e0005172. doi: 10.1371/journal.pntd.0005172. PLoS Negl Trop Dis. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. | Russells viper venom (RVV) was known to clot blood many years ago. Bridging the Gap between Alzheimer's Disease and Alzheimer's-like Diseases in Animals. Presynaptically acting phospholipase A2 from Vipera ammodytes venom. 2018 Feb 23;9:145. doi: 10.3389/fphar.2018.00145. A potent heterodimeric PLA2 neurotoxin (designated a Russtoxin) was found in the venoms of all Russell's vipers except Daboia russelli (Sri Lanka and South India). Toxicon. A major lethal factor of the venom of Burmese Russell's viper (Daboia russelli siamensis): isolation, N-terminal sequencing and biological activities of daboiatoxin. Silva A, Kuruppu S, Othman I, Goode RJ, Hodgson WC, Isbister GK. D. r. siamensis (Thailand and Burma) and D. r. russelli (Pakistan) represent one type whose venom contains PLA2S having an Asn residue at the N-terminus, while D. r. pulchella (South India and Sri Lanka) represents the other type, whose venom contains PLA2S with a N-terminal residue Ser. Gubensek F, Liang NS, Pungercar J, Strukelj B, Curin-Serbec V, Krizaj I. Ann N Y Acad Sci. | Hypopituitarism following envenoming by Russell's vipers (Daboia siamensis and D. russelii) resembling Sheehan's syndrome: first case report from Sri Lanka, a review of the literature and recommendations for endocrine management. NLM eCollection 2016 Dec. Neurotoxicity in Sri Lankan Russell's Viper (Daboia russelii) Envenoming is Primarily due to U1-viperitoxin-Dr1a, a Pre-Synaptic Neurotoxin. eCollection 2018. COVID-19 is an emerging, rapidly evolving situation. The venom obtained from the Russell viper (Vipera russelli) contains enzymes that directly activate coagulation factors V and X, bypassing the activation of factors VII, VIII, IX, XI, and XII, and, therefore, the effect of deficiencies or inhibitors of these factors. de Souza JM, Goncalves BDC, Gomez MV, Vieira LB, Ribeiro FM. A potent heterodimeric PLA2 neurotoxin (designated a Russtoxin) was found in the venoms of all Russell's vipers except Daboia russelli (Sri Lanka and South India). The single species, D. russelii (commonly known as Russell's viper), is found in Asia throughout the Indian subcontinent, much of Southeast Asia, southern China and Taiwan. QJM. | RVV came to be useful in laboratory tests for blood clotting factors V, X, prothrombin and phospholipid. HHS 2019 Apr 3;20(7):1664. doi: 10.3390/ijms20071664. USA.gov. Get the latest public health information from CDC: https://www.coronavirus.gov.
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